Investment and Acquisitions Trends in Medical Equipment Market 2011

1 Table of Contents 4 1.1 List of Tables 7 1.2 List of Figures 7 2 Introduction 8 2.1 GBI Research Report Guidance 9 3 M&A Deals by Type 10 3.1 Medical Equipment Market, Global Financial Deals 10 4 M&A Deals by Value Range, 2006–2009 12 4.1 Mergers and Acquisitions 13 5 M&A Deals by Geography 14 6 Global Medical Equipment Market: Competitive Assessment 15 6.1 Medical Equipment, M&A Opportunities and Risk Evaluation 15 6.2 Key Takeaway 17 7 M&A Key Deals in 2010 18 7.1 Novartis Completes Acquisition of Additional 52% Stake in Alcon from Nestle 18 7.1.1 Overview 18 7.1.2 Deal Rationale 18 7.1.3 Deal Analysis 19 7.1.4 Company Profile 20 7.2 Merck Completes the Acquisition of Millipore 21 7.2.1 Overview 21 7.2.2 Deal Rationale 21 7.2.3 Deal Analysis 21 7.2.4 Company Profile 21 7.3 Covidien Completes Acquisition of ev3 for $2.6 Billion 22 7.3.1 Overview 22 7.3.2 Deal Rationale 22 7.3.3 Deal Analysis 22 7.3.4 Company Profile 23 7.4 St. Jude Medical Acquires AGA Medical Holdings for $1.3 Billion 23 7.4.1 Overview 23 7.4.2 Deal Rationale 24 7.4.3 Deal Analysis 24 7.4.4 Company Profile 25 7.5 Medtronic Completes Acquisition of Invatec and Affiliated Companies 25 7.5.1 Overview 25 7.5.2 Deal Rationale 25 7.5.3 Deal Analysis 26 7.5.4 Company Profile 26 7.6 St. Jude Medical Completes Acquisition of Light Lab Imaging 27 7.6.1 Overview 27 7.6.2 Deal Rationale 27 7.6.3 Deal Analysis 27 7.6.4 Company Profile 27 8 Mergers and Acquisitions in Top Five Markets 28 8.1 In Vitro Diagnosis 28 8.2 Siemens Medical Acquires Dade Behring 32 8.2.1 Overview 32 8.2.2 Deal Rationale 32 8.2.3 Deal Analysis 32 8.2.4 Company Profile 33 8.3 Roche Acquires Ventana Medical Systems 33 8.3.1 Overview 33 8.3.2 Deal Rationale 33 8.3.3 Deal Analysis 33 8.3.4 Company Profile 34 8.4 Siemens Medical Acquires Diagnostic Products Corporation 34 8.4.1 Overview 34 8.4.2 Deal Rationale 34 8.4.3 Deal Analysis 34 8.4.4 Company Profile 35 8.5 Inverness Medical Acquires Biosite 35 8.5.1 Overview 35 8.5.2 Deal Rationale 35 8.5.3 Deal Analysis 35 8.5.4 Company Profile 36 8.6 Orthopedic 37 8.7 Medtronic Acquires Kyphon 41 8.7.1 Overview 41 8.7.2 Deal Rationale 41 8.7.3 Deal Analysis 41 8.7.4 Company Profile 42 8.8 Reable Therapeutics Acquires DJO 42 8.8.1 Overview 42 8.8.2 Deal Rationale 42 8.8.3 Deal Analysis 43 8.8.4 Company Profile 43 8.9 Smith & Nephew Acquires Plus Orthopedics Holding 43 8.9.1 Overview 43 8.9.2 Deal Rationale 43 8.9.3 Deal Analysis 44 8.9.4 Company Profile 44 8.10 Zimmer Holdings Acquired Abbott Spine from Abbott Laboratories 44 8.10.1 Overview 44 8.10.2 Deal Rationale 44 8.10.3 Deal Analysis 45 8.10.4 Company Profile 46 8.11 Cardiovascular 47 8.11.1 Market Drivers 48 8.12 Boston Scientific Acquires Guidant 50 8.12.1 Overview 50 8.12.2 Deal Rationale 50 8.12.3 Deal Analysis 51 8.12.4 Company Profile 52 8.13 Teleflex Acquires Arrow International 52 8.13.1 Overview 52 8.13.2 Deal Rationale 52 8.13.3 Deal Analysis 53 8.13.4 Company Profile 53 8.14 Cardinal Health Acquires VIASYS Healthcare 54 8.14.1 Overview 54 8.14.2 Deal Rationale 54 8.14.3 Deal Analysis 54 8.14.4 Company Profile 54 8.15 Ophthalmic 55 8.15.1 Market Drivers 56 8.16 Abbott Laboratories Acquires Advanced Medical Optics 57 8.16.1 Overview 57 8.16.2 Deal Rationale 57 8.16.3 Deal Analysis 58 8.16.4 Company Profile 59 8.17 Luxottica Group Acquires Oakley 59 8.17.1 Overview 59 8.17.2 Deal Rationale 60 8.17.3 Deals Analysis 60 8.17.4 Company Profile 60 8.18 Advanced Medical Optics Acquires Intralase 61 8.18.1 Overview 61 8.18.2 Deal Rationale 61 8.18.3 Deal Analysis 61 8.18.4 Company Profile 61 8.19 Drug Delivery Devices 62 8.19.1 Market Drivers 62 8.20 Hisamitsu Pharmaceutical Completes Acquisition of Noven Pharmaceuticals 63 8.20.1 Overview 63 8.20.2 Deal Rationale 63 8.20.3 Deals Analysis 63 8.20.4 Company Profile 63 8.21 Kimberly-Clark Completes Acquisition of I-Flow 64 8.21.1 Overview 64 8.21.2 Deal Rationale 64 8.21.3 Deal Analysis 65 8.21.4 Company Profile 66 8.22 Surmodics Acquires Brookwood Pharmaceuticals 66 8.22.1 Overview 66 8.22.2 Deal Rationale 66 8.22.3 Deal Analysis 66 8.22.4 Company Profile 67 9 Mergers and Acquisitions Trends in the Medical Equipment Market 2011- Appendix 68 9.1 Sources 68 9.2 Acronyms 68 9.3 Research Methodology 69 9.3.1 Secondary Research 69 9.3.2 Primary Research 69 9.3.3 Models 70 9.3.4 Forecasts 70 9.3.5 Expert Panels 70 9.4 Contact Us 70 9.5 Disclaimer 70

List of Tables Table 1: Mergers & Acquisitions, Global, Number of Deals by Value Range, 2006–2009 12 Table 2: Mergers & Acquisitions, Global, Deals by Geography, 2006–2009 14 Table 3: Cataract Surgery Devices Market, Global, Revenue ($bn), 2009–2016 19 Table 4: Peripheral Vascular Devices Market, Global, Revenue ($bn), 2009–2016 22 Table 5: AGA Medical Holdings Pipeline Products 24 Table 6: IVD Market, Global, Revenue ($bn), 2009-2016 28 Table 7: Orthopedic Devices Market, Global, Revenue ($bn), 2009–2016 37 Table 8: Spinal Surgery Market, Global, Revenue ($bn), 2009–2016 41 Table 9: Spinal Surgery Market, Global, Revenue ($bn), 2009–2016 45 Table 10: Global Cardiovascular Devices Market, Revenue ($bn), 2009–2016 47 Table 11: Interventional Cardiology Market, Global, Key Company Revenues ($m), 2009 51 Table 12: Ophthalmic Devices Market, Global, Revenue ($bn), 2009–2016 55 Table 13: Ophthalmic Devices Market, Global, Revenue ($bn), 2009–2016 58 Table 14: Drug Delivery Devices Market, Global, Revenue ($bn), 2009–2016 62 Table 15: Infusion Systems Market, Global, Revenue ($bn), 2009–2016 65

List of Figures Figure 1: Financial Deals, Global, Number of Deals by Type, 2006–2009 10 Figure 2: Mergers & Acquisitions, Global, Number of Deals by Value Range, 2006–2009 12 Figure 3: Medical Equipment, M&A Opportunities and Risk Evaluation, Global, by Category 15 Figure 4: Cataract Surgery Devices Market, Global, Revenue ($bn), 2009–2016 19 Figure 5: Peripheral Vascular Devices Market, Global, Revenue ($bn), 2009–2016 22 Figure 6: IVD Market, Global, Revenue ($bn), 2009-2016 28 Figure 7: In Vitro Diagnostics Market, Global, Pipeline Products Summary, 2010 31 Figure 8: Orthopedic Devices Market, Global, Revenue ($bn), 2009–2016 37 Figure 9: Orthopedic Devices Market, Global, Pipeline Products Summary, 2010 40 Figure 10: Spinal Surgery Market, Global, Revenue ($bn), 2009–2016 41 Figure 11: Spinal Surgery Market, Global, Revenue ($bn), 2009–2016 45 Figure 12: Global Cardiovascular Devices Market, Revenue ($bn), 2009–2016 47 Figure 13: Cardiovascular Devices, Global, Number of Pipeline Products, 2010 49 Figure 14: Interventional Cardiology Market, Global, Key Company Share (%), 2009 51 Figure 15: Acquisition of Arrow International Transforms Teleflex’s Product Portfolio 53 Figure 16: Ophthalmic Devices Market, Global, Revenue ($bn), 2009–2016 55 Figure 17: Ophthalmic Devices Market, Global, Revenue ($bn), 2009–2016 58 Figure 18: Drug Delivery Devices Market, Global, Revenue ($bn), 2009–2016 62 Figure 19: Infusion Systems Market, Global, Revenue ($bn), 2009–2016 65

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