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Articles by Calder Qimat |
1. Navitoclax phase II study 58 Among 62 evaluable
March 12, 2012
Navitoclax 923564-51-6, buy Navitoclax, Navitoclax & more.">Navitoclax those carrying the HER2 Ins774YVMA insertion mutation, but not in those with KRAS mutations.48...
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2. ABT-263 with advanced lung adenocarcinoma
March 12, 2012
boring the L858R/T790M double mutant, and in models dependent on HER2 overexpression.47 Afatinib 40–50 mg/day was evaluated in a single-arm phase II trial (LUX-Lung 2) in patients with advanced lung adenocarcinomas harboring activating EGFR mutations.49 Target accrual was 120 patients, with a total ...
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3. MG-132 in inhibiting
March 12, 2012
which can be blocked by the HDAC inhibitor MS-275.44 Notably, MG-132 133407-82-6, buy MG-132, MG-132 treating...
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4. Cyclin-dependent kinase inhibitor Perifosine
March 06, 2012
Over expression of EGFR has been demonstrated in the bulk , and may possibly be associated to superior T stage and existence of nodal disease. Perifosine overexpression has also been demonstrated to be a predictor of survival.
Treatment of tumor cells in vitro with anti-EGFR antibody induces...
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5. SB 431542 TGF-beta inhibitor electronic charts
March 06, 2012
Erlotinib is a tyrosine kinase inhibitor SB 431542 influencing the expression of epidermal development aspect in lung tumours. A huge randomized medical trial identified an total survival gain of 2. months in individuals handled with erlotinib compared to placebo , however individuals in this trial ...
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6. Danusertib comparison ABT-869 Linifanib ABT-869 FLT-3 inhibitor
March 02, 2012
Following tumor formation, creatures were randomized based on tumor volumes and given vehicle control, cetuximab alone, afatinib alone, or cetuximab plus afatinib. After a 3 week period, the therapy regimen of cetuximab plus afatinib produced a 76.5% decrease in cetuximab-resistant tumor volumes in ...
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7. Mocetinostat vaccine responses and myeloma-specific immuneresponses
March 02, 2012
This study was designed to determine whether Mocetinostat could increase vaccine responses and bring about myeloma-specific immuneresponses when used in combination with the pneumococcal Taxol 7-valent conjugatevaccine (PCV; Prevnar??, Wyeth Pharmaceuticals Inc., Philadelphia, PA), avaccine conjugat...
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8. Patients using Mocetinostat, SGI-1776 and SB939
March 02, 2012
This study was designed to determine whether Mocetinostat could increase vaccine responses and bring about myeloma-specific immuneresponses when used in combination with the pneumococcal Taxol 7-valent conjugatevaccine (PCV; Prevnar??, Wyeth Pharmaceuticals Inc., Philadelphia, PA), avaccine conjugat...
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9. PLX-4032, PF-2341066 and Bortezomib Chemical Libraries
March 01, 2012
Our previous data has demonstrated that Asian patients did equally well, but the total follow-up duration was limited PLX-4032. Therefore, this follow-up study aimed to look at the long-term outcome and side effects profile of our patients. This was an observational study. All patients with CML in t...
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10. PTC is increased in subjects confronted with radiations Vorinostat
March 01, 2012
PTC presents most commonly concerning 30 and 50 years of age, with a female/male percentage of 2-3: 1. Second hand smoke of PTC is increased in subjects confronted with radiations Vorinostat. The increasing incidence associated with thyroid cancer is associatedwith a higher number of advanced diseas...
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