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Biological databases have become vital tools for the study of the life sciences. It provides access to large repository of information required for variety of purposes by the researchers and scientists. For instance, in genomics (study of genes and their functions), there is high requirement of biological data. Gene expression data analysis or microarray analysis are important techniques of study of genes. However, it cannot be achieved without access to biological databases. Biological Databases A biological database is a large data, presented in organized manner containing life sciences information, gathered from scientific experiments, published literature, computational analysis, high throughput experiment technology. These databases contain information about genomics, metabolomics, proteomics, Microarray Analysis, Gene Expression Data Analysis and phylogenetics. The information contained in these databases includes gene structure, function, localization and clinical effects of mutations and similarities of biological sequences and structures. These databases are associated with computerized software to update, query and retrieve components of the database. Database can be simple as well as advanced. For instance, simple database may be comprised of a single file having records with same set of information. For a biological database to be beneficial for the researchers, it should meet two important requirements. It should provide easy access to the information provided and a reliable way to retrieve specific information needed to answer a particular biological question. The importance of these databases is increasing day by day as lots of bioinformatics work depends upon the technology of the databases. There are some public repositories and others are private ones used by the research groups involved in genes mapping projects. The most important aspect here is to make these databases accessible through open channels like web. Some popular Biological Databases GenBank GenBank refers to Genetic Sequence Databank that is the largest and fastest growing repositories of known genetic sequences. This easily accessible database contains a simple file structure that can be read by humans and machines as well. Apart from having sequence data, it also contains other information such as accession numbers, genes names, reference to the published literature and phylogenetic classification. ExPlain™ Analysis System It is tool for data and sequence analysis that is created to investigate the regulation of gene expression. It is presents in huge edition along with plant targeted edition required by agricultural researchers. A tool for data and sequence analysis designed to investigate the regulation of gene expression. ExPlain is offered in a mammalian focused edition along with a plant targeted edition for agricultural researchers. EMBL Comprehensive database of DNA and RNA sequences, The EMBL Nucleotide Sequence Database is collected from scientific literature and patent applications. It is directly submitted from researchers. Moreover, its data collection is done in associating with GenBank (USA) and the DNA Database of Japan (DDBJ). PROTEOME™ It is collection of protein databases providing disease, drug, and biomarker and pathway information. It provides comprehensive data. Main requirements for the public data services Data quality, supporting data, timeliness and cross –referencing are important requisites of a good biological databases. To Read more information about Gene Expression Data Analysis you can visit us at http://www.biobase-international.com Author of this article is expert in writing articles about Biological Databases, and gene expression data. He also written many articles about molecular and metabolic information and pathway analysis.
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