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Science analgesic ibuprofen taking four points - drugs - pharmaceutical industries by big tree





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Science analgesic ibuprofen taking four points - drugs - pharmaceutical industries by
Article Posted: 06/26/2010
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Science analgesic ibuprofen taking four points - drugs - pharmaceutical industries


 
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In 1968, the beginning of ibuprofen in the UK, because both anti-inflammatory, anti-rheumatic efficacy, and efficacy, Adverse reactions Such as aspirin and paracetamol fairly, quickly became the backbone of the market products. However, as antipyretic analgesic anti-inflammatory drugs, such as the gastrointestinal tract caused by adverse reactions, the key is how to scientifically take.

Antipyretic, analgesic, anti-inflammatory drugs indispensable in our daily lives, but there are data show that long-term use of such drugs to patients, about 10% to 25% of people may occur peptic ulcer, which can be less than 1% of serious complications, such as gastrointestinal bleeding or perforation; and the United States, the data also showed that oral administration of antipyretic analgesics mortality, second only to AIDS , Diabetes , Leukemia, malignant melanoma.

Ibuprofen as a anti-inflammatory drugs on the market Pillar Drugs One of the anti-inflammatory pain, cold, and many other drugs in the compound has the ingredients. See the above data, some people may worry: These drugs can also eat it? In fact, such worries are unnecessary. The results show, OTC dose of ibuprofen is relatively safe.

Ibuprofen three major advantages 1 relative safety, the World Health Organization recommends children
In all antipyretic analgesics, the World Health Organization recommends only acetaminophen (paracetamol) and ibuprofen as a safe and effective antipyretic drugs used in pediatrics, can be seen in the normal rational use of drugs, under the premise can rest assured it is taking.

2 effective control of persistent high fever, are used for high fever
The same as antipyretics in the body temperature higher than 39.2 , the dose of ibuprofen than with paracetamol is more effective and more lasting than the cooling time. Precisely because the special effects, ibuprofen most cases for sustained high fever and no rebate.

3 strong analgesic effect, 16-32 times stronger than aspirin
Advantage lies in its superior analgesic effect stronger than aspirin, 16 to 32 times, commonly used in all kinds of arthritis, pain, postoperative pain and Cancer Of pain.

TIPS1 - why good analgesic effects of ibuprofen?
Because it can inhibit the making "pain" to enlarge the prostaglandins. Prostaglandin and body pain, caused by heat, inflammation, can cause local tissue redness, swelling, fever, so that "pain" signal amplification, while ibuprofen and other non-steroidal anti-inflammatory drugs can inhibit the body cyclooxygenase (COX ), thus inhibiting prostaglandin synthesis, in order to relieve pain.

Addition to inhibiting prostaglandin synthesis, the ibuprofen can inhibit leukocyte activity and lysosomal release, thereby reducing the partial sciatic nerve on pain induced by bradykinin and other substances in pain sensitivity, but also help to relieve pain.

TIPS2 - What is prostaglandin? Prostaglandins is human and animals, a class of unsaturated fatty acids with a variety of physiological functions of the active substance, which enables smooth muscle excitability, decreased blood pressure. Because it is found in semen, was conceived by the prostate may be secreted, so as prostaglandins. But in fact, "the prostate secretion" is a misnomer, has now demonstrated that prostaglandins in semen from the seminal vesicle and prostaglandin in a large class of endocrine.

Ibuprofen, to refer to age, body mass index

As antipyretic analgesics speaking, the risk of adverse reactions associated with the dose, the relative more closely. In small doses, under the premise of short-term use of drugs, much less adverse reactions, but long-term, a large number of applications, the occurrence of gastrointestinal side effects such as the probability increases. Therefore, when the need in the application of ibuprofen should refer to age, weight and other indicators.

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