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4-Nitrophenyl Chloroformate impact on the environment by Wendy zong





Article Author Biography
4-Nitrophenyl Chloroformate impact on the environment by
Article Posted: 12/09/2009
Article Views: 187
Articles Written: 333
Word Count: 360
Article Votes: 0
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4-Nitrophenyl Chloroformate impact on the environment


 
Business,Business Opportunities,Health

Description: 4-Nitrophenyl Chloroformate GC 96% or 4-Nitrophenyl Chloroformate Titration 98%
Synonym: Chloroformic Acid 4-Nitrophenyl Ester
CAS: 7693-46-1
Assay: =96% (GC) ,98%(Titration)
Appearance: white or off-white crystal
Molecular: ClCO2C6H4NO2
Application: Anti-HIV as Pharmaceutical Intermediates

Health hazard: the mucous membrane and skin stimulation, causing methemoglobinemia.

Acute poisoning: Patients may have headache, dizziness, fatigue, skin and mucous membrane cyanosis, finger numbness and other symptoms. In severe cases, there may be chest tightness, shortness of breath, palpitations and even heart rhythm disorders, coma, convulsions, respiratory paralysis. And sometimes can cause hemolytic anemia, liver damage.
Chronic poisoning: in headache, fatigue, insomnia, memory loss and other neurological wasting syndrome; a chronic hemolysis, they can include jaundice, anemia; can cause toxic hepatitis.
Two, toxicology information and environmental behavior toxicity: it is highly toxic. Acute toxicity: LD50420mg/kg (rat oral); 16000mg/kg (free percutaneous) hazardous characteristics: case of fire, combustible high fever. Reactions can occur with strong oxidants. Subject to heat decomposition, produce toxic gases of nitrogen oxides and chlorides. Corrosive. Combustion (decomposition) products: carbon monoxide, carbon dioxide, nitrogen oxides, hydrogen chloride.
3. Emergency Monitoring Methods: direct inlet gas chromatography
4. Laboratory monitoring methods: gas chromatography (GB13194-91, Water), naphthyl ethylenediamine hydrochloride colorimetry, "Determination of harmful substances in the air" (second edition), Hang Shi-ping editor
5. environmental standards: China (TJ36-79) workshop in the air of harmful substances maximum allowable concentration 1mg/m3 [Paper] the former East Germany (1977) air quality standards 0.04mg/m3 China (to be issued) to drink with source water of harmful substances maximum allowable concentration of 0.05mg / L of China (GB8978-1996) Integrated Wastewater Discharge Standard 1 0.5mg / L 2 1.0mg / L 3 5.0mg / L
From: timepharm


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