|
Fluorine-containing pyridine intermediates into the hot At present, China has developed and has been put into mass production of the quinolone antibacterial drugs are mainly norfloxacin, ciprofloxacin, ofloxacin, enoxacin, lomefloxacin and fluorine Rosa magnitude. Including norfloxacin, ciprofloxacin, ofloxacin produce the largest, accounting for fluoroquinolone antibacterial agents of domestic production of 98%. Quinolones are generally synthetic fluorine-containing fluorine-containing benzene ring after quinoline piperazine compounds (or methyl piperazine) derived from condensation. Because China's abundant reserves of fluorite, which is the world's production of fluorine-containing drugs and intermediates, one of the largest countries, with more than 80% of the export supply of fluorine-containing intermediates. Overall, the development of China-fluorobenzene intermediate class early, the current excess production capacity generally; Benzotrifluoride the development of late pharmaceutical intermediates class in recent years, fast development; while for heterocyclic aromatic compounds, especially fluorinated pyridine class, our present, only the individual research units and production plants have a fluorine-containing pyridine intermediate synthesis technology, therefore, fluorine-containing pyridine intermediates will be the next few years, the domestic development of fluorine-containing intermediates, one of the main directions. For example: Chloromethyl Pivalate
Aminophenol big gap in China has become the world's largest Pharmaceutical Intermediates manufacturers of anti-inflammatory drugs, aspirin, paracetamol, and other types of output Junchao analgin million tons, phenacetin, aminopyrine, security other than the forest species for production of more than 1000 tons. At present, China's output of antipyretic analgesics has grown rapidly in the future will be expected to grow at a rate of about 8%. For the complete production of antipyretic analgesics intermediate output of large manufacturing enterprises more. With the growth of anti-inflammatory drugs, their intermediates have also gained considerable development.
Related Articles -
Pharmaceutical, Intermediates,
|
