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Ultrananocrystalline diamond-coated membranes show promise formedical implant applications by na b
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Ultrananocrystalline diamond-coated membranes show promise formedical implant applications by NA B
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Article Posted: 04/20/2014 |
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Ultrananocrystalline diamond-coated membranes show promise formedical implant applications |
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Business,Business News,Business Opportunities
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Posted: Jun 11th, 2012 Ultrananocrystalline diamond-coated membranes show promise formedical implant applications ( Nanowerk News ) Ultrananocrystalline diamond (UNCD) displays biological andmechanical properties that make it a promising choice for promotingepidermal cell migration on percutaneous implant surfaces.Percutaneous implants are commonly used for treatment of medicaland dental conditions. Biocompatibility of the implant materialplays a crucial role in preventing infections that cause prematurefailure. Recent studies have shown that microporous membranes can facilitatemigration of epidermal cells, enabling the development of a sealthat resists movement of fluid and microorganisms and thereforeimproving the implant life. A team of Center for Nanoscale Materials users from the Universityof North Carolina and North Carolina State University, working withthe Nanofabrication & Devices Group , devised a simple but innovative approach that combines both ofthese aspects simply by coating silicon nitride microporousmembranes with a conformal coating of ultrathin (~150 nm) UNCDfilms. The resulting membrane not only provides the required porousstructure, but also offers exceptional mechanical and biocompatibleproperties (see paper in Journal of the Minerals, Metals and Materials Society : "Ultrananocrystalline Diamond-Coated Microporous SiliconNitride Membranes for Medical Implant Applications" ). SEM image of AAO membrane coated with tungsten followed by UNCDexhibits 30-to 50-nm pore diameter The team demonstrated that their method also works on nanoporousanodized aluminum oxide (AAO) membranes that are coated with UNCDto reduce the pore size down to 30-50 nm. Scanning electronmicroscopy (SEM) and Raman spectroscopy were used to examine thepore structure and chemical bonding of the resulting membrane.Growth of human epidermal keratinocytes on uncoated and UNCD-coatedsilicon nitride microporous membranes was compared by using the3-(4,5-dimethylthiazol-2-yl) 2,5-diphenyltetrazolium bromide (MTT)assay. Both membranes displayed increased cell growth due to theirporosity, and the UNCD coating did not alter the viability of humanepidermal keratinocytes. Because of its exceptional chemical andmechanical properties, it is expected that UNCD will provide a morestable implant-tissue interface than silicon nitride. I am an expert from pvcsmartcard.com, while we provides the quality product, such as PVC Business Cards , Programmable Smart Card, Contactless Smart Card,and more.
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