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Proper use of drugs treating coronary stent Science - stents, coronary heart disease - the pharmace by na b
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Proper use of drugs treating coronary stent Science - stents, coronary heart disease - the pharmace by NA B
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| Article Posted: 01/23/2011 |
| Article Views: 129 |
| Articles Written: 2638 - MORE ARTICLES FROM THIS AUTHOR |
| Word Count: 693 |
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Proper use of drugs treating coronary stent Science - stents, coronary heart disease - the pharmace |
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The birth of drug and clinical application of stents in coronary heart disease treatment and reduce the incidence of restenosis has played a significant role. However, how to avoid stent thrombosis has become a new clinical problem. The clinical relevance of professional doctors, the correct selection and use of drugs support, scientific guidance to the patient continued to receive anti-platelet therapy, on both doctors and patients is essential?? This is the well-known experts in cardiac intervention, Southeast University Affiliated Hospital of Zhongshan University Director of Vascular Medicine Professor Ma Genshan recently held in Nanjing, "Jiangsu and Anhui provinces Clinical analysis of coronary stent thrombosis Conference" repeatedly emphasized content.
stent is not omnipotent Introduced, according to Professor Ma Genshan, coronary restenosis has been limited application of percutaneous coronary angioplasty is an important cause, although common stenting compared with balloon angioplasty can reduce the diameter greater than 3 mm of restenosis occurred, but the high rate of stent stenosis, and the development of drug stent restenosis can be said to control a major advance on. Currently, the domestic treatment of coronary intervention, stent application rate of 80% to 90%, further reducing restenosis after stenting in patients with rate, and reduced target lesion revascularization rate for domestic majority of patients with coronary heart disease has brought good news. However, the stent is not a panacea, it is still there are some adverse effects and application limitations. For example, delayed re-endothelialization of drug stents and polymer-coated lead to local vascular inflammation and allergic and late stent and poor adherence are likely to increase in late stent thrombosis events, lead to a new danger.
avoid excessive use of Professor Ma Genshan that for coronary heart disease, drug stent application is not all ice cold. If the excessive use of drugs in clinical support, would increase the occurrence of adverse events.
For 2.50 ~ 3.75 mm diameter blood vessels, length <30 mm of its native coronary artery lesions, stable or unstable myocardial ischemia, stent implantation of drug safety and efficacy has been proven to belong to class adaptation Permit (A-class level of evidence). In addition, randomized controlled clinical study also confirmed the drug stents in diabetic blood vessels, small vessel disease and bifurcation lesions, left main disease, multivessel disease, saphenous vein graft disease, chronic obstructive disease of complete and acute myocardial infarction complicated superior efficacy of disease treatment. Will be accepted for urgent major surgery, elderly patients and for various reasons can not tolerate long-term clopidogrel, aspirin in patients with dual antiplatelet therapy should not consider the use of stent. For the intervention after 12 months in need of invasive treatment or surgery in patients treated with balloon dilation or placement should be considered ordinary stent, and not to be implanted stent.
Clinical coronary intervention in support of universal concern about the safety of drug problem, more support should be emphasized that the proper use of drugs, including indications and rational use of the correct choice, standardized operations, improve quality of operation and stent implantation After the correct application of dual antiplatelet treatment strategy, the correct evaluation of the risk of stent implantation in patients benefit ratio.
persist more than 1 year after anticoagulant therapy
"Drugs to patients after stent under the guidance of doctors and persist in taking antiplatelet drugs. Because the anti-platelet therapy to prevent thrombosis can maximize ensure lasting cardiovascular flow." Professor Ma Genshan In particular, some stent thrombosis after stent implantation may be a year or longer after, once the early termination of antiplatelet therapy in patients, the risk of blood clots will increase dramatically. Once the formation of stent thrombosis, the treatment will significantly increase the difficulty, if not timely medical treatment can be life threatening.
New study abroad, should be used after stent implantation dual antiplatelet drugs for at least 12 months. High-risk patients need to take more time anti-platelet drugs, needs further study has confirmed. I am a professional writer from Components Electronic suppliers, which contains a great deal of information about led washer , keychain flashlights, welcome to visit!
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